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Filtered Search Results
Medchemexpress LLC FX-06 1mg | 88650-17-3 | 1MG
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FX-06 (Fibrin-derived peptide B 15-42) is a fibrin Bbeta chain-derived peptide FX-06 binds to VE-cadherin and inhibits leukocyte transmigration and initiates VE-cadherin-mediated signaling FX-06 can be used in the research of ischemia/reperfusion injury Dengue shock syndrome (DSS)[1 [2 [4
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Cambridge Isotope Laboratories 1 2 4 5 8-PentaCN (PCN-59) (unlabeled) 100 ug/mL in nonane 1 mL
1 2 4 5 8-PentaCN (PCN-59) (unlabeled) 100 ug/mL in nonane 1 mL
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Sigma Aldrich Fine Chemicals Biosciences Ethyl cinnamate 98 stabili1KG
REAGENT Ethyl cinnamate 98 stabili1KG
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eMolecules 82019-32-7 | 7-Bromo-1-methyl-1H-quinoxalin-2-one | MFCD10000855 | 250mg
Ambeed | 7-Bromo-1-methyl-1H-quinoxalin-2-one | 250mg | 600833751 | A206593 | 82019-32-7 | MFCD10000855 | 239.072 | C9H7BrN2O
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Medchemexpress LLC RGW-611 50mg | 6497-78-5 | 50MG
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RGW 611 is a morpholine derivative that enhances radiation-induced cell death of hypoxic V79-379A cells RGW 611 also stimulates fatty acid synthesis[1 [2
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Medchemexpress LLC DD-03-171 | 2366132-45-6 | 98.7% | 1 ML
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PROTAC BTK degrader supplied as a concentrated solution for use in biochemical and cellular research. Provided as a small-volume, high-concentration stock suitable for in vitro assays; reported purity supports use in assay development and preclinical studies.
- Provided as a 10 mM solution in DMSO, 1 mL.
- Induces selective degradation of Bruton's tyrosine kinase (BTK) in cellular models.
- High reported purity, suitable for biochemical and cell-based assays.
- Chemical formula C55H62N10O8 and molecular weight 991.14 g/mol.
- Packaged for research applications requiring small-volume, concentrated stocks.
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Medchemexpress LLC Methyl 3,3-dimethoxypropionate | 7424-91-1 | MFCD00010650 | ≥98.0% | 148.16 g·mol^-1 | C6H12O4 | 100 G
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Methyl 3,3-dimethoxypropionate is an organic methyl ester used as a building block and intermediate in organic synthesis and life-science research. It is commonly employed in the preparation of derivatives and in multi-step synthetic sequences where a protected aldehyde equivalent is required.
- High purity (≥98.0%) for research and synthesis.
- Serves as a methyl ester building block in organic synthesis.
- Useful as a protected aldehyde equivalent in multi-step syntheses.
- Available in multiple pack sizes for lab-scale work.
- Molecular formula C6H12O4 and molecular weight 148.16 g·mol^-1.
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Medchemexpress LLC DYB-03 | 2982792-85-6 | 99.5% | 479.56 | 1 ML
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DYB-03 is an orally active HIF-1α/EZH2 inhibitor. It inhibits the migration, invasion, and angiogenesis of lung cancer cells and HUVECs both in vitro and in vivo. Additionally, DYB-03 induces apoptosis in A549 and H460 cells that are resistant to 2-ME2 and GSK126.
- Oral active HIF-1α/EZH2 inhibitor
- Inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs (in vitro and in vivo)
- Induces apoptosis in 2-ME2- and GSK126-resistant A549 and H460 cells
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Apexbio Technology LLC IAA-94 54197-31-8 25mg
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IAA-94 (CAS 54197-31-8) is a small-molecule inhibitor of epithelial chloride channels modulating cellular electrophysiological properties by disrupting chloride ion transport Experimental studies have demonstrated that IAA-94 can interfere with interactions involving the negative factor (Nef) protein during infection indicating its capacity to modulate Nef-mediated processes Due to its specificity in targeting chloride channels IAA-94 is widely utilized in investigations of ion channel-related signaling pathways in tumor cells and serves as a valuable tool in studies of cell electrophysiology and infection mechanisms
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 50 MG
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Ro 31-9790 is a synthetic matrix metalloproteinase (MMP) inhibitor used as a research reagent to probe MMP activity, protease-mediated ectodomain shedding, and related cellular pathways. It is supplied as a high-purity solid for laboratory studies and includes handling and storage recommendations to preserve stability.
- High purity, suitable for biochemical and cellular assays.
- Molecular weight 315.41 g/mol and formula C15H29N3O4 for compound identification.
- Off-white to light yellow solid appearance for easy visual confirmation.
- Recommended storage at 4°C; protect from light and store under inert gas; in solvent, store at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO with supplier-provided concentration guidance for assay preparation.
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Medchemexpress LLC KRAS G12D-IN-31 | 3024060-23-6 | 98.5% | 698.80 | 1 MG
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KRAS G12D-IN-31 is a potent inhibitor of KRAS G12D, demonstrating an IC50 of less than 100 nM. It effectively inhibits the proliferation of various RAS-dependent cells, including those with KRASG12C, KRAS G12D, KRASG12V, and KRASWT mutations. This compound is a valuable tool for research into conditions such as non-small cell lung cancer, gastric cancer, colon cancer, and malignant melanoma.
- Potent KRAS G12D inhibitor
- Inhibits proliferation of RAS-dependent cells
- Suitable for research on non-small cell lung cancer
- Suitable for research on gastric cancer
- Suitable for research on colon cancer
- Suitable for research on malignant melanoma
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Medchemexpress LLC 2(1H)-Phthalazineacetamide, 4-(4-chlorophenyl)-N-(4-fluorophenyl)-1-oxo- | 684234-60-4 | 98.6% | 407.82 | 25 MG
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2(1H)-Phthalazineacetamide, 4-(4-chlorophenyl)-N-(4-fluorophenyl)-1-oxo- | 684234-60-4 | 98.6% | 407.82 | 25 MG
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Medchemexpress LLC Methyl 3,3-dimethoxypropionate | 7424-91-1 | MFCD00010650 | ≥98.0% | 148.16 g/mol | C6H12O4 | 250 G
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Methyl 3,3-dimethoxypropionate is an organic methyl ester used as a reagent and synthetic intermediate in organic and medicinal chemistry. The molecule features a dimethoxy (acetal)-protected propionate unit that acts as a masked aldehyde equivalent, enabling controlled deprotection and further functionalization. It is supplied as a colorless liquid at research-grade purity for laboratory synthesis and method development.
- Functions as a masked aldehyde equivalent in synthesis.
- Provides an acetal-protected propionate for selective transformations.
- Facilitates ester hydrolysis and downstream derivatization.
- Suitable for multistep organic and medicinal chemistry workflows.
- Available in research-scale quantities with high purity.
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 25 MG
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Ro 31-9790 is a synthetic metalloproteinase (MMP) inhibitor used in research to block proteolytic shedding of cell-surface molecules such as L-selectin and TNF-α. It demonstrates sub-micromolar to low-micromolar activity in human and mouse immune cells and is supplied as a high-purity solid for laboratory experiments.
- Potent inhibition of L-selectin shedding in immune cells.
- Active against TNF-α shedding in monocytes.
- High purity suitable for biochemical and cellular assays.
- Available in multiple pack sizes including small-milligram quantities.
- Provided with datasheet, SDS, and COA for quality traceability.
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